Top nonstop routes from MSL
- Charlotte (CLT)2-3/day · 1 airline · 378 mi
- Pensacola (PNS)2×/wk · 1 airline · 296 mi
- Tupelo (TUP)weekly · 1 airline · 74 mi
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Nonstop route map
Where can you fly from MSL?
Explore direct flights from Northwest Alabama Regional Airport in Muscle Shoals. Filter by airline, domestic or international routes, distance, and frequency.
Schedule data as of June 14, 2026
Use the destination list below to select a route with a keyboard or screen reader.
MSL to CLTCharlotteCharlotte/Douglas International Airport - United States
2-3/day378 miEst. ~1h 22m
Airline
3destinations shown
1country
1airline
2.6/dayscheduled frequency
Every nonstop destination
Direct flights from MSL
| Destination | Airlines | Frequency | Distance | Flight time |
|---|---|---|---|---|
| 2-3/day | 378 mi | Est. ~1h 22m | ||
| 2×/wk | 296 mi | Est. ~1h 12m | ||
| weekly | 74 mi | Est. ~44m |
Travel search guide
Where can I travel from MSL?
Northwest Alabama Regional Airport in Muscle Shoals has nonstop flights to 3 destinations across 1 country. FlightQ counts direct, nonstop routes from MSL; connecting itineraries are not included. The current schedule shows about 2.6/day nonstop departures.
Popular places you can fly nonstop from MSL include Charlotte (CLT), Pensacola (PNS), and Tupelo (TUP). The route map also covers destinations in United States.
Airlines flying from MSL
American Airlines3 destinations
Domestic and international options
From MSL, FlightQ currently shows 3 domestic destinations and 0 international destinations.
Longest nonstop route
The longest listed nonstop route from MSL is MSL to CLT in Charlotte, about 378 miles.
Current schedule layer
FlightQ groups current departure rows from MSL by destination and airline, so these counts reflect nonstop schedule detail rather than broad route claims.