Knoxville→OrlandoNonstop Flight TimeTYS–ISM

Knoxville (Mc Ghee Tyson Airport) to Orlando (Kissimmee Gateway Airport).

Direct flights from TYS to ISM have an estimated flight time of about 1h 42m, based on the 541-mile great-circle distance. Our current captured departure sample includes weekly across 1 captured airline, with PSSEP appearing most often in that sample. Captured departure times run from 11:15 to 11:15 local time.

Methodology: airline, aircraft, terminal, and departure-time details come from the rolling scheduled-departures window for TYS to ISM, last seen June 15, 2026. Frequency uses 1 scheduled departures across 1 observed day; flight time is estimated from great-circle distance until this route has enough tracked flights for an observed average. Provider coverage can miss operators on some routes, so confirm live timetables before booking.